By Jeffrey M. Drazen (auth.), Zeliha Yazici, Giancarlo C. Folco, Jeffrey M. Drazen, Santosh Nigam, Takao Shimizu (eds.)

ISBN-10: 1461348315

ISBN-13: 9781461348313

This quantity, the complaints of the twelfth foreign convention on Advances in Prostaglandin, Leukotriene and different Bioactive Lipid examine: simple technology and medical functions, held August 25-29, 2002, in Istanbul, Turkey, discusses advances in bioactive lipid examine with specified cognizance to melanoma, cardiovascular illnesses, gastrointestinal ailments and respiration ailments. particular themes lined contain the position of leukotrienes and lipoxins in irritation, the cytochrome P450 pathway, the genetics and genomics of bioactive lipids, lipid peroxidation, apoptosis, angiogenesis, isoprostanes, receptors and inhibitors, cyclooxygenase and lipoxygenase pathways and inhibitors, prostaglandin synthases and receptor signaling, phospholipases and inhibitors.

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Additional resources for Advances in Prostaglandin, Leukotriene, and other Bioactive Lipid Research: Basic Science and Clinical Applications

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The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils. J Biol Chern 264:12885-12889 Wheelan P, Murphy RC. Quantitation of 5-lipoxygenase products by electrospray mass spectrometry: effect of ethanol on zymosan-stimulated production of 5lipoxygenase products by human neutrophils. Anal Biochern 1997; 244:110-115. Chapter #8 FIRM ADHESION OF NEUTROPHILS TO CEREBRAL VASCULAR ENDOTHELIUM "IN VIVO": A ROLE FOR CYSLEUKOTRIENES Chiara Carnini, Gabriela Constantin, Barbara Rossi, Marco De Curtis and Giancarlo Folco Introduction Interactions between neutrophils (PMNL) and endothelial cells (EC) are involved in pathological alterations of cerebral blood vessel functions, leading to circulatory disturbances such as stroke [1].

23. 24. 25. 26. 27. 28. 5 Drazen 1M, Yandava C, Dube L, Szczerback N, Hippensteel R, Pillari A et al. Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment Nature Genetics 1999; 22:170-172. Asano K, Shiomi T, Hasegawa N, Nakamura H, Kudo H, Matsuzaki T et aI. Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LTl antagonist, in Japanese patients with moderate asthma. Pharmacogenetics 2002; 12:1-6. Bleecker ER, Welch MJ, Weinstein SF, Kalberg C, Johnson M, Edwards L et al.

13. 14. 15. 16. 17. Drazen JM, Austen KF. Effects of intravenous administration of slow-reacting substance of anaphylaxis, histamine, bradykinin , and prostaglandin F2alpha on pulmonary mechanics in the guinea pig. J Clin Invest 1974; 53: 1679-1685. Brocklehurst WE. The release of histamine and the formation of a slow-reacting substance (SRS-A) during anaphylactic shock. J Physiol (Lond) 1960; 151:416-435. Murphy RC, Hammarstrom S, Samuelsson B. Leukotriene C: a slow-reacting substance from murine mastocytoma cells.

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Advances in Prostaglandin, Leukotriene, and other Bioactive Lipid Research: Basic Science and Clinical Applications by Jeffrey M. Drazen (auth.), Zeliha Yazici, Giancarlo C. Folco, Jeffrey M. Drazen, Santosh Nigam, Takao Shimizu (eds.)


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