By Jayanthi N. Koneru MD, Lance W. Weathers MD, Michael Lesch MD (auth.), Mun K. Hong MD, Eyal Herzog MD, FACC (eds.)
Acute coronary syndrome (ACS) impacts hundreds of thousands of sufferers each year and calls for fast analysis and remedy. seriously, given the getting older worldwide inhabitants, ACS is determined to develop into a fair higher scientific challenge, not just for the emergency room and cardiology physicians, yet for all experts treating the older inhabitants susceptible to ACS. Advances within the remedy of ACS can justifiably be one in all the nice achievements of recent medication. The evolution of therapy options represents a extraordinary success, yet there's an pressing have to train these experts treating the high-risk inhabitants. This useful algorithm-based guide addresses the prognosis and remedy of those sufferers and is designed for the scientific body of workers occupied with the triage and administration of ACS patients.
Acute Coronary Syndrome: Multidisciplinary and Pathway-Based Approach bargains scientific counsel to all trainees and non-medical experts and gives a framework for more matured employees to control ACS sufferers successfully. The authors have compiled a wealth of clinically worthwhile instruments and data drawn from their event at St. Luke’s-Roosevelt health facility middle in manhattan, making this e-book a accomplished evidence-based source that enables readers to extend their wisdom and permits swift analysis and therapy of sufferers with ACS.
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Additional resources for Acute Coronary Syndrome: Multidisciplinary and Pathway-Based Approach
Proposed that the initial step in acute coronary thrombosis is the development 4. Epidemiology and Pathophysiology of ACS 27 Inflammation 1. Matrix breakdown 2. Tissue factor expression Shoulder of fibrous cap Apoptosis Fibrous cap Lipid core 1. Reduced matrix synthesis 2. Lipid and tissue factor deposition VULNERABLE PLAQUE 1. Large lipid core 2. Thin fibrous cap 3. Inflammation and apoptosis 4. Positive remodeling with moderate luminal stenosis 5. 1. Components of a vulnerable plaque and a magnified view of the shoulder region with events contributing to plaque rupture.
It is completed by the admitting resident in lieu of a traditional admission note and serves as a data collection device. The medical intern and the attending physician are required to write the more traditional admission notes. The second page of the admission form (Fig. 2) is a composite of admission information based on our chest pain pathway. This form reproduces the format of the chest pain pathway as described in Chapter 2. It emphasizes the concept of risk stratiﬁcation of patients presenting with chest pain using the acronym PAIN (priority risk, advanced risk, intermediate risk, and negative/low risk), which reﬂects the patient’s initial risk stratiﬁcation upon admission.
Such areas of endothelial desquamation form the nidus of a platelet thrombus with subsequent platelet adhesion and activation . Although many episodes of ACS are caused by the disruption or erosion of plaque, other mechanisms that alter myocardial oxygen supply and demand such as vasoconstriction and Prinzmetal angina can occur. In the setting of ACS, vasoconstriction may occur as a response to a mildly dysfunctional endothelium near the culprit lesion or due to the deep arterial damage or plaque disruption.
Acute Coronary Syndrome: Multidisciplinary and Pathway-Based Approach by Jayanthi N. Koneru MD, Lance W. Weathers MD, Michael Lesch MD (auth.), Mun K. Hong MD, Eyal Herzog MD, FACC (eds.)